ZMYND8 promotes the growth and metastasis of hepatocellular carcinoma by promoting HK2-mediated glycolysis
C Dou, H Mo, T Chen, J Liu, Y Zeng, S Li, C Guo… - … -Research and Practice, 2021 - Elsevier
The bromodomain protein zinc finger MYND-type containing 8 (ZMYND8) plays a critical
role in human breast cancer. However, the expression and biological function of ZMYND8 in
hepatocellular carcinoma (HCC) are poorly understood. In this study, ZMYND8 expression
was found to be elevated in HCC based on the cancer genome atlas (TCGA) and gene
expression omnibus (GEO) databases. Next, we confirmed that ZMYND8 was frequently
overexpressed in HCC tissues compared with adjacent non-tumor tissues. The up-regulated …
role in human breast cancer. However, the expression and biological function of ZMYND8 in
hepatocellular carcinoma (HCC) are poorly understood. In this study, ZMYND8 expression
was found to be elevated in HCC based on the cancer genome atlas (TCGA) and gene
expression omnibus (GEO) databases. Next, we confirmed that ZMYND8 was frequently
overexpressed in HCC tissues compared with adjacent non-tumor tissues. The up-regulated …