Enrichment and characterization of human and murine pulmonary mesenchymal progenitor cells (MPC)
M Summers, K Helm, SM Majka - Stem Cells and Tissue Repair: Methods …, 2020 - Springer
M Summers, K Helm, SM Majka
Stem Cells and Tissue Repair: Methods and Protocols, 2020•SpringerTissue resident mesenchymal progenitor cells (MPC) are important regulators of tissue
repair or regeneration, remodeling, inflammation, and angiogenesis. Here we describe a
technology used to define, isolate, and characterize a population of resident lung MPC in
both human and mouse explanted tissue. The definition of this population using a defined
set of markers facilitates the repeatable isolation of a mesenchymal subpopulation
population by flow cytometry and the subsequent translational study of this specific cell type …
repair or regeneration, remodeling, inflammation, and angiogenesis. Here we describe a
technology used to define, isolate, and characterize a population of resident lung MPC in
both human and mouse explanted tissue. The definition of this population using a defined
set of markers facilitates the repeatable isolation of a mesenchymal subpopulation
population by flow cytometry and the subsequent translational study of this specific cell type …
Abstract
Tissue resident mesenchymal progenitor cells (MPC) are important regulators of tissue repair or regeneration, remodeling, inflammation, and angiogenesis. Here we describe a technology used to define, isolate, and characterize a population of resident lung MPC in both human and mouse explanted tissue. The definition of this population using a defined set of markers facilitates the repeatable isolation of a mesenchymal subpopulation population by flow cytometry and the subsequent translational study of this specific cell type and function.
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