The effects of Assisted Reproductive Technologies on genomic imprinting in the placenta

EA Rhon-Calderon, LA Vrooman, L Riesche… - Placenta, 2019 - Elsevier
The placenta is a complex and poorly understood organ, which serves as the connection
between the mother and the developing fetus. Genomic imprinting, defined as a regulatory
process resulting in the expression of a gene in a parent-of-origin-specific manner, plays an
important role in fetal development and placental function. Disturbances that occur during
the establishment and maintenance of imprinting could compromise the placenta and fetus,
and ultimately, offspring health. Assisted Reproductive Technologies (ART) have been …