[HTML][HTML] Mat-8, a Novel Phospholemman-like Protein Expressed in Human Breast Tumors, Induces a Chloride Conductance in Xenopus Oocytes (∗)
BW Morrison, JR Moorman, GC Kowdley… - Journal of Biological …, 1995 - ASBMB
We recently identified a novel 8-kDa transmembrane protein, Mat-8, that is expressed in a
subset of murine breast tumors. We have now cloned a cDNA encoding the human version
of Mat-8 and show that it is expressed both in primary human breast tumors and in human
breast tumor cell lines. The extracellular and transmembrane domains of Mat-8 are
homologous to those of phospholemman (PLM), the major plasmalemmal substrate for
cAMP-dependent protein kinase and protein kinase C in several different tissues. PLM …
subset of murine breast tumors. We have now cloned a cDNA encoding the human version
of Mat-8 and show that it is expressed both in primary human breast tumors and in human
breast tumor cell lines. The extracellular and transmembrane domains of Mat-8 are
homologous to those of phospholemman (PLM), the major plasmalemmal substrate for
cAMP-dependent protein kinase and protein kinase C in several different tissues. PLM …