Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)
P Lertkiatmongkol, D Liao, H Mei, Y Hu… - Current opinion in …, 2016 - journals.lww.com
P Lertkiatmongkol, D Liao, H Mei, Y Hu, PJ Newman
Current opinion in hematology, 2016•journals.lww.comOwing to the unique ability of antibodies that bind the membrane proximal region of the
extracellular domain to trigger conformational changes leading to affinity modulation and
homophilic adhesion strengthening, PECAM-1 might be an attractive target for treating
vascular permeability disorders.
extracellular domain to trigger conformational changes leading to affinity modulation and
homophilic adhesion strengthening, PECAM-1 might be an attractive target for treating
vascular permeability disorders.
Summary
Owing to the unique ability of antibodies that bind the membrane proximal region of the extracellular domain to trigger conformational changes leading to affinity modulation and homophilic adhesion strengthening, PECAM-1 might be an attractive target for treating vascular permeability disorders.
Lippincott Williams & Wilkins