FXYD3 protein involved in tumor cell proliferation is overproduced in human breast cancer tissues
H Yamamoto, K Okumura, S Toshima… - Biological and …, 2009 - jstage.jst.go.jp
H Yamamoto, K Okumura, S Toshima, K Mukaisho, H Sugihara, T Hattori, M Kato, S Asano
Biological and Pharmaceutical Bulletin, 2009•jstage.jst.go.jpBiol. Pharm. Bull. 32(7): 1148-1154 (2009) Page 1 FXYD3 was originally identified as one of the
gene products (mRNAs) highly expressed in murine mammary tumors induced by the
transgenic neu or ras but not induced by myc or int-2 oncogenes.In human, FXYD3 mRNA was
overexpressed in breast cancer cell lines and primary breast cancers,2) and also in prostate
and pancreatic cancers.Suppression of FXYD3 expression by the small interfering RNA (siRNA)
or antisense transfection caused a significant decrease in cellular proliferation of prostate and …
gene products (mRNAs) highly expressed in murine mammary tumors induced by the
transgenic neu or ras but not induced by myc or int-2 oncogenes.In human, FXYD3 mRNA was
overexpressed in breast cancer cell lines and primary breast cancers,2) and also in prostate
and pancreatic cancers.Suppression of FXYD3 expression by the small interfering RNA (siRNA)
or antisense transfection caused a significant decrease in cellular proliferation of prostate and …
MATERIALS AND METHODS
Cell Lines Human breast cancer, MDA-MB-453, gastric cancers, MKN1, MKN28, MKN45, MKN74, pancreatic cancer, T3M-4, colon cancer, CACO-2, bladder cancer, T24, lung cancers, RERF-LC-AI, A549, brain astrocytoma,
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