Association of epigenetic age acceleration with risk factors, survival, and quality of life in patients with head and neck cancer
Purpose Epigenetic age acceleration (EAA) is robustly linked with mortality and morbidity.
This study examined risk factors of EAA and its association with overall survival (OS),
progression-free survival (PFS), and quality of life (QOL) in patients with head and neck
cancer (HNC) receiving radiation therapy. Methods and Materials Patients without distant
metastasis were enrolled and followed before and at the end of radiation therapy and at 6
and 12 months after radiation therapy. EAA was calculated with DNAmPhenoAge at all 4 …
This study examined risk factors of EAA and its association with overall survival (OS),
progression-free survival (PFS), and quality of life (QOL) in patients with head and neck
cancer (HNC) receiving radiation therapy. Methods and Materials Patients without distant
metastasis were enrolled and followed before and at the end of radiation therapy and at 6
and 12 months after radiation therapy. EAA was calculated with DNAmPhenoAge at all 4 …
