Philadelphia chromosome-negative chronic myeloproliferative neoplasms: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

AM Vannucchi, T Barbui, F Cervantes… - Annals of …, 2015 - annalsofoncology.org
According to the 2008 World Health Organization (WHO) classification, classical
Philadelphia chromosome/BCR-ABL negative chronic myeloproliferative neoplasms (MPNs)
include polycythaemia vera (PV), essential thrombocythaemia (ET) and primary
myelofibrosis (PMF)[1]. The reported worldwide annual incidence rate of MPNs ranges from
0.44 to 5.87/105, with the lowest incidence being reported in Japan and Israel [2]. These
great ranges may reflect racial/geographic differences as well as differences in study design …