[HTML][HTML] Guarding the perimeter: protection of the mucosa by tissue-resident memory T cells
LS Cauley, L Lefrancois - Mucosal immunology, 2013 - Elsevier
Mucosal tissues are continually bombarded with infectious agents seeking to gain entry into
the body. The absence of a tough physical exterior layer surrounding these tissues creates a
unique challenge for the immune system, which manages to provide broad protection
against a plethora of different organisms with the aid of special adaptations that augment
immunity at these vulnerable sites. For example, specialized populations of memory T
lymphocytes reside at initial sites of pathogen entry into the body, where they provide an …
the body. The absence of a tough physical exterior layer surrounding these tissues creates a
unique challenge for the immune system, which manages to provide broad protection
against a plethora of different organisms with the aid of special adaptations that augment
immunity at these vulnerable sites. For example, specialized populations of memory T
lymphocytes reside at initial sites of pathogen entry into the body, where they provide an …
