[HTML][HTML] Structure and function of mammalian cilia
P Satir, ST Christensen - Histochemistry and cell biology, 2008 - Springer
P Satir, ST Christensen
Histochemistry and cell biology, 2008•SpringerIn the past half century, beginning with electron microscopic studies of 9+ 2 motile and 9+ 0
primary cilia, novel insights have been obtained regarding the structure and function of
mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a
large number of cellular signaling pathways, sometimes coupling the signaling to ciliary
motility or alternatively to cell division and differentiation. This view has had unanticipated
consequences for our understanding of developmental processes and human disease.
primary cilia, novel insights have been obtained regarding the structure and function of
mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a
large number of cellular signaling pathways, sometimes coupling the signaling to ciliary
motility or alternatively to cell division and differentiation. This view has had unanticipated
consequences for our understanding of developmental processes and human disease.
Abstract
In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes coupling the signaling to ciliary motility or alternatively to cell division and differentiation. This view has had unanticipated consequences for our understanding of developmental processes and human disease.
Springer