[HTML][HTML] Cellular and molecular mechanisms of mitochondrial function

LD Osellame, TS Blacker, MR Duchen - Best practice & research Clinical …, 2012 - Elsevier
Mitochondria are membrane bound organelles present in almost all eukaryotic cells.
Responsible for orchestrating cellular energy production, they are central to the
maintenance of life and the gatekeepers of cell death. Thought to have originated from
symbiotic ancestors, they carry a residual genome as mtDNA encoding 13 proteins essential
for respiratory chain function. Mitochondria comprise an inner and outer membrane that
separate and maintain the aqueous regions, the intermembrane space and the matrix …