Interferon-like virus-inhibitor induced in human leukocytes by phytohemagglutinin

EF Wheelock - Science, 1965 - science.org
EF Wheelock
Science, 1965science.org
Phytohemagglutinin, an extract of the kidney bean, Phaseolus vulgaris, induces in human
leukocyte cultures an inhibitor of the cytopathic effects of Sindbis virus. The physicochemical
and biological properties of this virus-inhibitor are similar to those of interferon induced by
Newcastle disease virus, except for an instability at p H 2 and 10 and at 56° C.
Phytohemagglutinin, an extract of the kidney bean, Phaseolus vulgaris, induces in human leukocyte cultures an inhibitor of the cytopathic effects of Sindbis virus. The physicochemical and biological properties of this virus-inhibitor are similar to those of interferon induced by Newcastle disease virus, except for an instability at pH 2 and 10 and at 56°C.
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