Placental glucose transporter (GLUT)-1 is down-regulated in preeclampsia

BP Lüscher, C Marini, MS Joerger-Messerli, X Huang… - Placenta, 2017 - Elsevier
Introduction Transplacental fetal glucose supply is predominantly regulated by glucose
transporter-1 (GLUT1). Altered expression and/or function of GLUT1 may affect the
intrauterine environment, which could compromise fetal development and may contribute to
fetal programming. To date it is unknown whether placental GLUT1 is affected by
preeclampsia, which is often associated with intrauterine growth restriction (IUGR). We
addressed the hypothesis that preeclampsia leads to decreased expression and function of …