Differential effects of influenza virus NA, HA head, and HA stalk antibodies on peripheral blood leukocyte gene expression during human infection

KA Walters, R Zhu, M Welge, K Scherler, JK Park… - MBio, 2019 - Am Soc Microbiol
In this study, we examined the relationships between anti-influenza virus serum antibody
titers, clinical disease, and peripheral blood leukocyte (PBL) global gene expression during
presymptomatic, acute, and convalescent illness in 83 participants infected with 2009
pandemic H1N1 virus in a human influenza challenge model. Using traditional statistical
and logistic regression modeling approaches, profiles of differentially expressed genes that
correlated with active viral shedding, predicted length of viral shedding, and predicted …

[PDF][PDF] Differential effects of influenza virus NA, HA head, and HA stalk antibodies on peripheral blood leukocyte gene expression during human infection. mBio 10 …

KA Walters, R Zhu, M Welge, K Scherler, JK Park… - 2019 - academia.edu
In this study, we examined the relationships between anti-influenza virus serum antibody
titers, clinical disease, and peripheral blood leukocyte (PBL) global gene expression during
presymptomatic, acute, and convalescent illness in 83 participants infected with 2009
pandemic H1N1 virus in a human influenza challenge model. Using traditional statistical
and logistic regression modeling approaches, profiles of differentially expressed genes that
correlated with active viral shedding, predicted length of viral shedding, and predicted …