Prenatally diagnosed severe CDH: mortality and morbidity remain high
MA Coughlin, NL Werner, R Gajarski… - Journal of pediatric …, 2016 - Elsevier
Purpose This study sought to evaluate prenatal markers' ability to predict severe congenital
diaphragmatic hernia (CDH) and assess this subgroup's morbidity and mortality. Methods A
retrospective review was performed between 2006 and 2014. Prenatal criteria for severe
CDH included: liver herniation, lung-to-head ratio (LHR)< 1 on prenatal ultrasound and/or
observed-to-expected LHR (o/eLHR)< 25%, and/or observed-to-expected total lung volume
(o/eTLV)< 25% on fetal MRI. Postnatal characteristics included: mortality, ECMO utilization …
diaphragmatic hernia (CDH) and assess this subgroup's morbidity and mortality. Methods A
retrospective review was performed between 2006 and 2014. Prenatal criteria for severe
CDH included: liver herniation, lung-to-head ratio (LHR)< 1 on prenatal ultrasound and/or
observed-to-expected LHR (o/eLHR)< 25%, and/or observed-to-expected total lung volume
(o/eTLV)< 25% on fetal MRI. Postnatal characteristics included: mortality, ECMO utilization …
