[HTML][HTML] The microbiota, the immune system and the allograft

ML Alegre, RB Mannon, PJ Mannon - American Journal of Transplantation, 2014 - Elsevier
The microbiota represents the complex collections of microbial communities that colonize a
host. In health, the microbiota is essential for metabolism, protection against pathogens and
maturation of the immune system. In return, the immune system determines the composition
of the microbiota. Altered microbial composition (dysbiosis) has been correlated with a
number of diseases in humans. The tight reciprocal immune/microbial interactions
complicate determining whether dysbiosis is a cause and/or a consequence of immune …