Circulating interferon in cytomegalovirus infected bone-marrow-transplant recipients and in infants with congenital cytomegalovirus disease

A Rhodes-Feuillette, M Canivet… - Journal of interferon …, 1992 - liebertpub.com
A Rhodes-Feuillette, M Canivet, H Champsaur, E Gluckman, MC Mazeron, J Peries
Journal of interferon research, 1992liebertpub.com
In a study concerning five CMV-infected bone-marrow-transplant recipients, five congenital
CMV diseases and appropriate controls, presence of high levels of circulating interferon
(IFN) was demonstrated exclusively during the course of CMV disease. This interferon was
predominantly" immune" or gamma interferon (γ-IFN). These results suggest that during
CMV disease the interferon compartment of the immune response is modified.
Abstract
In a study concerning five CMV-infected bone-marrow-transplant recipients, five congenital CMV diseases and appropriate controls, presence of high levels of circulating interferon (IFN) was demonstrated exclusively during the course of CMV disease. This interferon was predominantly "immune" or gamma interferon (γ-IFN). These results suggest that during CMV disease the interferon compartment of the immune response is modified.
Mary Ann Liebert