Enteroendocrine cells: a site of 'taste'in gastrointestinal chemosensing
C Sternini, L Anselmi, E Rozengurt - Current Opinion in …, 2008 - journals.lww.com
C Sternini, L Anselmi, E Rozengurt
Current Opinion in Endocrinology, Diabetes and Obesity, 2008•journals.lww.comTaste-signaling molecules expressed in the gastrointestinal mucosa might participate in the
functional detection of nutrients and harmful substances in the lumen and prepare the gut to
absorb them or initiate a protective response. They might also participate in the control of
food intake through the activation of gut–brain neural pathways. These findings provide a
new dimension to unraveling the regulatory circuits initiated by luminal contents of the
gastrointestinal tract.
functional detection of nutrients and harmful substances in the lumen and prepare the gut to
absorb them or initiate a protective response. They might also participate in the control of
food intake through the activation of gut–brain neural pathways. These findings provide a
new dimension to unraveling the regulatory circuits initiated by luminal contents of the
gastrointestinal tract.
Summary
Taste-signaling molecules expressed in the gastrointestinal mucosa might participate in the functional detection of nutrients and harmful substances in the lumen and prepare the gut to absorb them or initiate a protective response. They might also participate in the control of food intake through the activation of gut–brain neural pathways. These findings provide a new dimension to unraveling the regulatory circuits initiated by luminal contents of the gastrointestinal tract.
Lippincott Williams & Wilkins