Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy
JM Hofstra, H Debiec, CD Short, T Pellé… - Journal of the …, 2012 - journals.lww.com
The phospholipase A 2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy. The technique for measuring antibodies against PLA 2 R and
the relationship between antibody titer and clinical characteristics are not well established.
Here, we measured anti-PLA 2 R (aPLA 2 R) antibody titer and subclass in a well defined
cohort of 117 Caucasian patients with idiopathic membranous nephropathy and nephrotic-
range proteinuria using both indirect immunofluorescence testing (IIFT) and ELISA. We …
membranous nephropathy. The technique for measuring antibodies against PLA 2 R and
the relationship between antibody titer and clinical characteristics are not well established.
Here, we measured anti-PLA 2 R (aPLA 2 R) antibody titer and subclass in a well defined
cohort of 117 Caucasian patients with idiopathic membranous nephropathy and nephrotic-
range proteinuria using both indirect immunofluorescence testing (IIFT) and ELISA. We …