Abstract The 2011 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice
Guideline for Glomerulonephritis (GN) aims to assist practitioners caring for adults and
children with GN. Guideline development followed an explicit process of evidence review
and appraisal. The guideline contains chapters on various glomerular diseases: steroid-
sensitive nephrotic syndrome in children; steroid-resistant nephrotic syndrome in children;
minimal-change disease; idiopathic focal segmental glomerulosclerosis; idiopathic …

Glomerulonephritis (GN) is an important cause of morbidity and mortality in patients of all
ages throughout the world. Because these disorders are relatively rare, it is difficult to
perform randomized clinical trials to define optimal treatment for many of the specific
glomerulopathies. In the absence of high-grade evidence to guide the care of glomerular
diseases, in June 2012, KDIGO (Kidney Disease: Improving Global Outcomes) published an
international clinical guideline for GN. The Work Group report represents an important …