Overcoming obstacles to developing new analgesics
CJ Woolf - Nature medicine, 2010 - nature.com
Nature medicine, 2010•nature.com
Despite substantial investment by the pharmaceutical industry over several decades, there
has been little progress in developing new, efficacious and safe analgesics. As a result,
many large pharmaceutical companies are leaving the area of pain medication.
Nevertheless, the chances of success could increase if analgesic drug development strategy
changed. To achieve such a paradigm shift we must understand why development of drugs
for pain relief is so challenging.
has been little progress in developing new, efficacious and safe analgesics. As a result,
many large pharmaceutical companies are leaving the area of pain medication.
Nevertheless, the chances of success could increase if analgesic drug development strategy
changed. To achieve such a paradigm shift we must understand why development of drugs
for pain relief is so challenging.
Abstract
Despite substantial investment by the pharmaceutical industry over several decades, there has been little progress in developing new, efficacious and safe analgesics. As a result, many large pharmaceutical companies are leaving the area of pain medication. Nevertheless, the chances of success could increase if analgesic drug development strategy changed. To achieve such a paradigm shift we must understand why development of drugs for pain relief is so challenging.
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