Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: a randomized controlled trial
AL Zietman, ML DeSilvio, JD Slater, CJ Rossi… - Jama, 2005 - jamanetwork.com
ContextClinically localized prostate cancer is very prevalent among US men, but recurrence
after treatment with conventional radiation therapy is common. ObjectiveTo evaluate the
hypothesis that increasing the radiation dose delivered to men with clinically localized
prostate cancer improves disease outcome. Design, Setting, and PatientsRandomized
controlled trial of 393 patients with stage T1b through T2b prostate cancer and prostate-
specific antigen (PSA) levels less than 15 ng/mL randomized between January 1996 and …
after treatment with conventional radiation therapy is common. ObjectiveTo evaluate the
hypothesis that increasing the radiation dose delivered to men with clinically localized
prostate cancer improves disease outcome. Design, Setting, and PatientsRandomized
controlled trial of 393 patients with stage T1b through T2b prostate cancer and prostate-
specific antigen (PSA) levels less than 15 ng/mL randomized between January 1996 and …