The pulsatile secretion of hormones from the mammalian pituitary gland drives a wide range
of homeostatic responses by dynamically altering the functional set-point of effector tissues.
To accomplish this, endocrine cell populations residing within the intact pituitary display
large-scale changes in coordinated calcium-spiking activity in response to various
hypothalamic and peripheral inputs. Although the pituitary gland is structurally
compartmentalized into specific and intermingled endocrine cell networks, providing a clear …