Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.
RG Holloway, I Shoulson, S Fahn, K Kieburtz… - Archives of …, 2004 - europepmc.org
Archives of neurology, 2004•europepmc.org
Objective To compare initial treatment with pramipexole vs levodopa in early Parkinson
disease, followed by levodopa supplementation, with respect to the development of
dopaminergic motor complications, other adverse events, and functional and quality-of-life
outcomes. Design
disease, followed by levodopa supplementation, with respect to the development of
dopaminergic motor complications, other adverse events, and functional and quality-of-life
outcomes. Design
Objective
To compare initial treatment with pramipexole vs levodopa in early Parkinson disease, followed by levodopa supplementation, with respect to the development of dopaminergic motor complications, other adverse events, and functional and quality-of-life outcomes.
Design
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