[HTML][HTML] Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma
F Baran-Marszak, M Boukhiar, S Harel… - …, 2010 - ncbi.nlm.nih.gov
F Baran-Marszak, M Boukhiar, S Harel, C Laguillier, C Roger, R Gressin, A Martin, R Fagard…
Haematologica, 2010•ncbi.nlm.nih.govBackground The deregulation of several transcription factors contribute to the aggressive
course of mantle cell lymphoma. This study focuses on survival signals emanating from the
tumor environment and involving the signal transducer and activator of transcription (STAT)
3 through cytokines or antigen recognition.
course of mantle cell lymphoma. This study focuses on survival signals emanating from the
tumor environment and involving the signal transducer and activator of transcription (STAT)
3 through cytokines or antigen recognition.
Abstract
Background
The deregulation of several transcription factors contribute to the aggressive course of mantle cell lymphoma. This study focuses on survival signals emanating from the tumor environment and involving the signal transducer and activator of transcription (STAT) 3 through cytokines or antigen recognition.
ncbi.nlm.nih.gov
