Where are the gaps in asthma research? A counter-perspective
MJ Holtzman - Journal of allergy and clinical immunology, 2003 - jacionline.org
Reviews and feature articles development of allergy and the development of asthma are
often dissociated as well7 and linkage to candidate genes for atopy might be absent in large
segments of the asthmatic population. 8 Moreover, treatment aimed at selective blockade of
TH2 pathways has not yet proved to be efficacious in asthma. 9 Nonetheless, these
discrepancies are generally ascribed to the complexity of the allergic response. Even given
this diversity, however, an allergenbased proposal for pathogenesis provides little …
often dissociated as well7 and linkage to candidate genes for atopy might be absent in large
segments of the asthmatic population. 8 Moreover, treatment aimed at selective blockade of
TH2 pathways has not yet proved to be efficacious in asthma. 9 Nonetheless, these
discrepancies are generally ascribed to the complexity of the allergic response. Even given
this diversity, however, an allergenbased proposal for pathogenesis provides little …
