A neurological syndrome associated with orthostatic hypotension: a clinical-pathologic study

GM Shy, GA Drager - AMA Archives of Neurology, 1960 - jamanetwork.com
Introduction Perhaps, with the exception of adrenal insufficiency, 1, 2 postural hypotension is
coincident with involvement of the nervous system. 3, 4 Many such cases are secondary to
disorders like diabetes, syphilis, and other systemic diseases, which also affect the central or
peripheral nervous system. 4-12 On exclusion of such disorders, however, one is left with an
idiopathic orthostatic hypotension, which is almost invariably accompanied by clinical
manifestation of nervous system involvement. Such patients may show wide swings in blood …