Expression of betacellulin and epidermal growth factor receptor in hepatocellular carcinoma: implications for angiogenesis
WS Moon, HS Park, KH Yu, MY Park, KR Kim, KY Jang… - Human pathology, 2006 - Elsevier
Hepatocellular carcinoma (HCC) is becoming one of the common malignant tumors
worldwide and is characterized by high vascularity. Angiogenesis (formation of new
microvessels) is critical for growth and progression of various human solid tumors.
Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family, and its signal
action is mediated through EGF receptors (EGFR). In this study, to understand the role of
BTC in relation to EGFR in HCC, we examined localization, expression, and involvement in …
worldwide and is characterized by high vascularity. Angiogenesis (formation of new
microvessels) is critical for growth and progression of various human solid tumors.
Betacellulin (BTC) is a member of the epidermal growth factor (EGF) family, and its signal
action is mediated through EGF receptors (EGFR). In this study, to understand the role of
BTC in relation to EGFR in HCC, we examined localization, expression, and involvement in …
