Dendritic cells (DC) are the professional antigen presenting cells of the immune system.
Therefore, several clinical studies have been initiated in which tumor antigen-loaded DC are
used as a vaccine to boost an immune response against malignant tumors in patients with
cancer. A prerequisite for DC used in these vaccination studies is not only that they are
grown under “Good Manufacturing Practice” but equally important that they retain their
functional properties. In an extensive study, various conditions were tested to optimize the …