Early events in M-CSF receptor signaling
RP Bourette, LR Rohrschneider - Growth factors, 2000 - Taylor & Francis
RP Bourette, LR Rohrschneider
Growth factors, 2000•Taylor & FrancisThe M-CSF receptor (M-CSFR) is expressed in monocytes-macrophages and their
progenitors, and drives growth and development of this blood cell lineage. The M-CSFR is a
member of a small family of growth factor receptors exhibiting related structures but distinct
tissue-specific functions. This review discusses the early molecular events in the M-CSF
signaling mechanisms, positive signals, negative signals, the possible organization of
individual signaling pathways, and the problem of achieving specificity in the signal …
progenitors, and drives growth and development of this blood cell lineage. The M-CSFR is a
member of a small family of growth factor receptors exhibiting related structures but distinct
tissue-specific functions. This review discusses the early molecular events in the M-CSF
signaling mechanisms, positive signals, negative signals, the possible organization of
individual signaling pathways, and the problem of achieving specificity in the signal …
The M-CSF receptor (M-CSFR) is expressed in monocytes-macrophages and their progenitors, and drives growth and development of this blood cell lineage. The M-CSFR is a member of a small family of growth factor receptors exhibiting related structures but distinct tissue-specific functions. This review discusses the early molecular events in the M-CSF signaling mechanisms, positive signals, negative signals, the possible organization of individual signaling pathways, and the problem of achieving specificity in the signal transduction mechanism.
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