[HTML][HTML] The enigmatic parietal epithelial cell is finally getting noticed: a review
T Ohse, JW Pippin, AM Chang, RD Krofft, JH Miner… - Kidney international, 2009 - Elsevier
T Ohse, JW Pippin, AM Chang, RD Krofft, JH Miner, MR Vaughan, SJ Shankland
Kidney international, 2009•ElsevierAlthough the normal glomerulus comprises four resident cell types, least is known about the
parietal epithelial cells (PECs). This comprehensive review addresses the cellular origin of
PECs, discusses the normal structure and protein makeup of PECs, describes PEC function,
and defines the responses to injury in disease and how these events lead to clinical events.
The data show that PECs have unique properties and that new functions are being
recognized such as their role in differentiating into podocytes during disease.
parietal epithelial cells (PECs). This comprehensive review addresses the cellular origin of
PECs, discusses the normal structure and protein makeup of PECs, describes PEC function,
and defines the responses to injury in disease and how these events lead to clinical events.
The data show that PECs have unique properties and that new functions are being
recognized such as their role in differentiating into podocytes during disease.
Although the normal glomerulus comprises four resident cell types, least is known about the parietal epithelial cells (PECs). This comprehensive review addresses the cellular origin of PECs, discusses the normal structure and protein makeup of PECs, describes PEC function, and defines the responses to injury in disease and how these events lead to clinical events. The data show that PECs have unique properties and that new functions are being recognized such as their role in differentiating into podocytes during disease.
Elsevier