[CITATION][C] [26] Generation of HIV-1 derived lentiviral vectors
A Follenzi, L Naldini - Methods in enzymology, 2002 - Elsevier
Gene transfer vectors derived from lentiviruses, such as human immunodeficiency virus 1
(HIV-1), are potentially important tools in clinical gene therapy for the treatment of a wide
array of inherited and acquired diseases, because of their ability to transduce several types
of target cells independently of their proliferation status both ex vivo and in vivo. Lentiviral
vectors (LV) are replication-defective, hybrid viral particles made by the core proteins and
enzymes of a lentivirus, and the envelope of a different virus, most often the vesicular …
(HIV-1), are potentially important tools in clinical gene therapy for the treatment of a wide
array of inherited and acquired diseases, because of their ability to transduce several types
of target cells independently of their proliferation status both ex vivo and in vivo. Lentiviral
vectors (LV) are replication-defective, hybrid viral particles made by the core proteins and
enzymes of a lentivirus, and the envelope of a different virus, most often the vesicular …
