[HTML][HTML] Basic fibroblast growth factor-induced neuronal differentiation of mouse bone marrow stromal cells requires FGFR-1, MAPK/ERK, and transcription factor AP-1
H Yang, Y Xia, SQ Lu, TW Soong, ZW Feng - Journal of biological chemistry, 2008 - ASBMB
It has been reported recently that bone marrow stromal cells (BMSCs) are able to
differentiate into various neural cells both in vivo and in vitro (Egusa, H., Schweizer, FE,
Wang, CC, Matsuka, Y., and Nishimura, I.(2005) J. Biol. Chem. 280, 23691–23697).
However, the underlying mechanisms remain largely unknown. In this report, we have
demonstrated that basic fibroblast growth factor (bFGF) alone effectively induces mouse
BMSC neuronal differentiation. These differentiated neuronal cells exhibit characteristic …
differentiate into various neural cells both in vivo and in vitro (Egusa, H., Schweizer, FE,
Wang, CC, Matsuka, Y., and Nishimura, I.(2005) J. Biol. Chem. 280, 23691–23697).
However, the underlying mechanisms remain largely unknown. In this report, we have
demonstrated that basic fibroblast growth factor (bFGF) alone effectively induces mouse
BMSC neuronal differentiation. These differentiated neuronal cells exhibit characteristic …
