Surface analyses and immune reactivities of major cell wall-associated proteins of group a streptococcus
JN Cole, RD Ramirez, BJ Currie, SJ Cordwell… - Infection and …, 2005 - Am Soc Microbiol
Infection and immunity, 2005•Am Soc Microbiol
ABSTRACT A proteomic analysis was undertaken to identify cell wall-associated proteins of
Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified,
66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-
reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-
associated proteins that are surface exposed.
Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified,
66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-
reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-
associated proteins that are surface exposed.
Abstract
A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed.
American Society for Microbiology