Antibodies of IgM subclass to phosphorylcholine and oxidized LDL are protective factors for atherosclerosis in patients with hypertension

J Su, A Georgiades, R Wu, T Thulin, U de Faire… - Atherosclerosis, 2006 - Elsevier
OBJECTIVE: To determine the importance of antibodies against phosphorylcholine (PC) and
oxidized low density lipoprotein (OxLDL) for development of atherosclerosis. METHODS
AND RESULTS: Two hundred and twenty six individuals with established hypertension
(diastolic pressure> 95mmHg) were from European Lacidipine Study on Atherosclerosis.
Antibodies of IgG and IgM subclass were tested by ELISA against PC (aPC), cupper-
oxidized (ox)-or malondialdehyde (MDA)-modified LDL. High-sensitivity C-reactive protein …