Cardiovascular aspects of anaphylaxis: implications for treatment and diagnosis
SGA Brown - Current opinion in allergy and clinical immunology, 2005 - journals.lww.com
Current opinion in allergy and clinical immunology, 2005•journals.lww.com
Current evidence supports use of the supine/Trendelenburg position, epinephrine by
intravenous infusion and aggressive volume resuscitation. If these fail, atropine should be
considered for severe bradycardia and potent vasoconstrictors may be useful. To confirm the
diagnosis of anaphylaxis, serial measurements of mast cell tryptase may be preferable to a
single measurement.
intravenous infusion and aggressive volume resuscitation. If these fail, atropine should be
considered for severe bradycardia and potent vasoconstrictors may be useful. To confirm the
diagnosis of anaphylaxis, serial measurements of mast cell tryptase may be preferable to a
single measurement.
Summary
Current evidence supports use of the supine/Trendelenburg position, epinephrine by intravenous infusion and aggressive volume resuscitation. If these fail, atropine should be considered for severe bradycardia and potent vasoconstrictors may be useful. To confirm the diagnosis of anaphylaxis, serial measurements of mast cell tryptase may be preferable to a single measurement.
Lippincott Williams & Wilkins