The possible role of bacterial superantigens in the pathogenesis of autoimmune disorders

J Schiffenbauer, J Soos, H Johnson - Immunology today, 1998 - cell.com
J Schiffenbauer, J Soos, H Johnson
Immunology today, 1998cell.com
The ability of superantigens (SAgs) to activate the immune system suggests that they may
play a role in the course of autoimmune disorders. Here, Joel Schiffenbauer and colleagues
review evidence from animal models of autoimmunity, as well as human data that support
this hypothesis, and propose a model for SAg involvement in autoimmune disorders.
Abstract
The ability of superantigens (SAgs) to activate the immune system suggests that they may play a role in the course of autoimmune disorders. Here, Joel Schiffenbauer and colleagues review evidence from animal models of autoimmunity, as well as human data that support this hypothesis, and propose a model for SAg involvement in autoimmune disorders.
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