Innate and adaptive mucosal immunity in protection against HIV infection
T Lehner - Vaccine, 2003 - Elsevier
T Lehner
Vaccine, 2003•ElsevierControl of the HIV pandemic requires an effective vaccine. The difficulties in developing a
preventive vaccine are generally believed to be due to the rapid rate of mutation of HIV that
escapes cytotoxic lymphocytes (CTL) and the problems in induction of neutralising
antibodies to wild strains of HIV. These difficulties should re-orientate vaccine strategy into
four somewhat neglected areas of immunisation.
preventive vaccine are generally believed to be due to the rapid rate of mutation of HIV that
escapes cytotoxic lymphocytes (CTL) and the problems in induction of neutralising
antibodies to wild strains of HIV. These difficulties should re-orientate vaccine strategy into
four somewhat neglected areas of immunisation.
Control of the HIV pandemic requires an effective vaccine. The difficulties in developing a preventive vaccine are generally believed to be due to the rapid rate of mutation of HIV that escapes cytotoxic lymphocytes (CTL) and the problems in induction of neutralising antibodies to wild strains of HIV. These difficulties should re-orientate vaccine strategy into four somewhat neglected areas of immunisation.
Elsevier
