[HTML][HTML] An IL13 coding region variant is associated with a high total serum IgE level and atopic dermatitis in the German multicenter atopy study (MAS-90)
X Liu, R Nickel, K Beyer, U Wahn, E Ehrlich… - Journal of Allergy and …, 2000 - Elsevier
Background: Allergic diseases are one of the major causes of morbidity in the developed
countries today, and the prevalence of these diseases is increasing steadily. Study of total
serum gE level is important in understanding the genetics of allergic iseases because IgE
levels are considered to be a crucial pathogenic component. IL-13 plays an important role in
the induction of IgE synthesis and in the pathogenesis of allergic diseases. Objective: We
sought to examine potential variation at the IL13 gene and estimate its effect on elevated IgE …
countries today, and the prevalence of these diseases is increasing steadily. Study of total
serum gE level is important in understanding the genetics of allergic iseases because IgE
levels are considered to be a crucial pathogenic component. IL-13 plays an important role in
the induction of IgE synthesis and in the pathogenesis of allergic diseases. Objective: We
sought to examine potential variation at the IL13 gene and estimate its effect on elevated IgE …