Regression of electrocardiographic left ventricular hypertrophy during antihypertensive treatment and the prediction of major cardiovascular events

PM Okin, RB Devereux, S Jern, SE Kjeldsen, S Julius… - Jama, 2004 - jamanetwork.com
ContextElectrocardiographic left ventricular hypertrophy (LVH) is a strong predictor of
cardiovascular (CV) morbidity and mortality. However, the predictive value of changes in the
magnitude of electrocardiographic LVH criteria during antihypertensive therapy remains
unclear. ObjectiveTo test the hypothesis that lesser severity of electrocardiographic LVH
during antihypertensive treatment is associated with decreased CV morbidity and mortality,
independent of blood pressure levels and reduction and treatment modality. Design, Setting …