Predictive value of ALT levels for histologic findings in chronic hepatitis C: a European collaborative study
The aim of this retrospective study was to determine the predictive value of alanine
aminotransferase (ALT) levels for histologic findings in patients with chronic hepatitis C virus
(HCV) infection. Data on 864 HCV RNA–positive patients were collected. ALT values were
obtained at the time of biopsy (before treatment), and normal ALT values were defined as
normal values obtained at serial evaluations during a 6-month period. Histologic results
were scored using the METAVIR system. Among all patients, 99% of those with elevated …
aminotransferase (ALT) levels for histologic findings in patients with chronic hepatitis C virus
(HCV) infection. Data on 864 HCV RNA–positive patients were collected. ALT values were
obtained at the time of biopsy (before treatment), and normal ALT values were defined as
normal values obtained at serial evaluations during a 6-month period. Histologic results
were scored using the METAVIR system. Among all patients, 99% of those with elevated …