The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS)
AM Beebe, DJ Cua, R de Waal Malefyt - Cytokine & growth factor reviews, 2002 - Elsevier
Interleukin-10 (IL-10) is an immunoregulatory cytokine that plays a crucial role in
inflammatory and immune reactions. It has potent anti-inflammatory and immunosuppressive
activities on myeloid cell functions which forms a solid basis for its use in acute and chronic
inflammatory diseases. Here, we discuss the role of IL-10 in autoimmune diseases and
examine its beneficial effects in cellular-based autoimmune diseases such as multiple
sclerosis (MS) or its involvement in humoral-based autoimmune diseases such as systemic …
inflammatory and immune reactions. It has potent anti-inflammatory and immunosuppressive
activities on myeloid cell functions which forms a solid basis for its use in acute and chronic
inflammatory diseases. Here, we discuss the role of IL-10 in autoimmune diseases and
examine its beneficial effects in cellular-based autoimmune diseases such as multiple
sclerosis (MS) or its involvement in humoral-based autoimmune diseases such as systemic …
