[HTML][HTML] Fibroblast Growth Factor-2 Can Mediate Cell Attachment by Linking Receptors and Heparan Sulfate Proteoglycans on Neighboring Cells (∗)
C Richard, JP Liuzzo, D Moscatelli - Journal of Biological Chemistry, 1995 - ASBMB
The myeloid 32D cell line, which grows in suspension and does not express FGF receptors
or heparan sulfate proteoglycans, was transfected with the cDNA encoding FGF receptor-1
(32D-flg cells). When co-cultured with glutaraldehyde-fixed Chinese hamster ovary (CHO)
cells, the 32D-flg cells remained in suspension in the absence of FGF-2 but attached to the
CHO monolayer in the presence of 10 ng/ml FGF-2. In contrast, 32D cells transfected with
the vector alone did not attach to the CHO monolayer in the presence of FGF-2. FGF-2 …
or heparan sulfate proteoglycans, was transfected with the cDNA encoding FGF receptor-1
(32D-flg cells). When co-cultured with glutaraldehyde-fixed Chinese hamster ovary (CHO)
cells, the 32D-flg cells remained in suspension in the absence of FGF-2 but attached to the
CHO monolayer in the presence of 10 ng/ml FGF-2. In contrast, 32D cells transfected with
the vector alone did not attach to the CHO monolayer in the presence of FGF-2. FGF-2 …
