[HTML][HTML] Direct cell adhesion to the angiopoietins mediated by integrins

TR Carlson, Y Feng, PC Maisonpierre… - Journal of Biological …, 2001 - ASBMB
Genetic ablation of angiopoietin-1 (Ang-1) or of its cognate receptor, Tie2, disrupts
angiogenesis in mouse embryos. The endothelial cells in growing blood vessels of Ang-1
knockout mice have a rounded appearance and are poorly associated with one another and
their underlying basement membranes (Dumont, DJ, Gradwohl, G., Fong, GH, Puri, MC,
Gertsenstein, M., Auerbach, A., and Breitman, ML (1994) Genes Dev. 8, 1897–1909; Sato,
TN, Tozawa, Y., Deutsch, U., Wolburg-Buchholz, K., Fujiwara, Y., Gendron-Maguire, M …