Differential age-change in the numbers of CD4+ CD45RA+ DC4+ CD29+ T cell subsets in human peripheral blood
M Utsuyama, K Hirokawa, C Kurashima… - Mechanisms of ageing …, 1992 - Elsevier
Peripheral blood mononuclear cells were obtained from people ranging in age from
newborn to 102 years old and analyzed by dual color flow cytometer in terms of number and
percentage of various subsets of T cells, B cells and natural killer cells (CD3, 4, 5, 8, 11b, 19,
20, 21, 25, 29, 45RA and 56). Numbers of T cells (CD3+ or CD5+ cells) significantly declined
at the 3rd decade as compared with those of younger people, stayed at a relatively constant
level between the 3rd and the 7th decade and gradually declined thereafter. In T cell …
newborn to 102 years old and analyzed by dual color flow cytometer in terms of number and
percentage of various subsets of T cells, B cells and natural killer cells (CD3, 4, 5, 8, 11b, 19,
20, 21, 25, 29, 45RA and 56). Numbers of T cells (CD3+ or CD5+ cells) significantly declined
at the 3rd decade as compared with those of younger people, stayed at a relatively constant
level between the 3rd and the 7th decade and gradually declined thereafter. In T cell …