Pathogenesis of human leukocyte antigen B27–positive arthritis: information from clinical materials
E Märker-Hermann, T Höhler - Rheumatic Disease Clinics of North …, 1998 - Elsevier
Acute reactive arthritis, spondyloarthropathy (SpA) in association with chronic inflammatory
bowel disease (IBD) and ankylosing spondylitis (AS), although differing in individual
presentation and in the natural course of disease, have in common a strong association with
human leukocyte antigen (HLA)-B27 and a possible involvement of other genetic and also
environmental factors. This group of related diseases belonging to the seronegative SpAs
represents the clearest example of HLA class 1–linked disease in humans. Several newly …
bowel disease (IBD) and ankylosing spondylitis (AS), although differing in individual
presentation and in the natural course of disease, have in common a strong association with
human leukocyte antigen (HLA)-B27 and a possible involvement of other genetic and also
environmental factors. This group of related diseases belonging to the seronegative SpAs
represents the clearest example of HLA class 1–linked disease in humans. Several newly …
