Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10 …
S Issazadeh, A Ljungdahl, B Höjeberg… - Journal of …, 1995 - Elsevier
The kinetics of mRNA expression in the central nervous system (CNS) for a series of
putatively disease-promoting and disease-limiting cytokines during the course of
experimental autoimmune encephalomyelitis (EAE) in Lewis rats were studied. Cytokine
mRNA-expressing cells were detected in cryosections of spinal cords using in situ
hybridization technique with synthetic oligonucleotide probes. Three stages of cytokine
mRNA expression could be distinguished:(i) interleukin (IL)-12, tumor necrosis factor (TNF) …
putatively disease-promoting and disease-limiting cytokines during the course of
experimental autoimmune encephalomyelitis (EAE) in Lewis rats were studied. Cytokine
mRNA-expressing cells were detected in cryosections of spinal cords using in situ
hybridization technique with synthetic oligonucleotide probes. Three stages of cytokine
mRNA expression could be distinguished:(i) interleukin (IL)-12, tumor necrosis factor (TNF) …
